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CA Topic

Transgenic Organisms

Brief Context

President Donald Trump recently made a mistaken claim that $8 million had been spent on making mice transgender, which was later corrected to transgenic mice.

Source Content

Syllabus :GS 3/Science and Tech  

In News

  • U.S. President Donald Trump recently made a mistaken claim that $8 million had been spent on “making mice transgender,” which was later corrected to “transgenic mice.” 

About 

  • Media reports clarified that the research involved hormone treatments for studies on hormone therapy, HIV vaccines, breast cancer, and other health areas—not for altering the gender of mice. 
  • Studies with transgenic mice have helped understand genetics, cancer, reproduction, and more. These mice are valuable in modeling diseases due to their genetic similarities to humans.

Transgenic organism

  • It  refers to an organism or cell whose genome has been altered by the introduction of one or more foreign DNA sequences from another species by artificial means.
  • Transgenic organisms are generated in the laboratory for research purposes.
Transgenic organism

Applications 

  • Transgenic animals have been used to study genetic processes, such as the role of DNA in carrying genetic information and the link between oncogenes and cancer.
  • Transgenic animals also help understand normal physiological processes and model human diseases for treatment development.
    • Animals like goats and cows are engineered to produce therapeutic proteins, such as insulin.
  • Transgenic crops have been produced that are resistant to infectious diseases and grow faster.
  • It is used in bioremediation to break down pollutants like oil spills and heavy metals.

Challenges

  • There are ethical concerns about animal welfare and the morality of genetic modification.
  • There are chances of Potential environmental or health impacts, such as unintended gene flow or allergic reactions.
  • The creation of transgenic organisms is expensive and technically challenging.

Conclusion and Way Forward 

  • Transgenic organisms offer great potential in medicine, agriculture, and environmental management but require careful handling of ethical, environmental, and regulatory concerns to ensure their responsible use.

Source :TH